Contents Leading articles Seeking a ‘peakless’ insulin: long-acting insulin analogues The management of erectile dysfunction in diabetes ( also available as 'Online PDF file' which can be read in Adobe Acrobat Reader, a no-cost program.) Clinical reviews ( also available as 'Online PDF file' which can be read in Adobe Acrobat Reader, a no-cost program.) Gluconeogenesis, glucose production and fasting glycaemia Improved glycaemic control with insulin aspart  Significance of non-traditional risk factors for CHD in diabetes: the ARIC study Epidural spinal cord electrical stimulation — can it play a role in critical lower limb ischaemia? UKPDS: effects of glycaemia and systolic blood pressure on micro- and macrovascular complications in Type 2 diabetes Calcium homeostasis in diabetic patients TGF-b and diabetic kidney disease Mode of inheritance of diabetic nephropathy Insulin pumps at night: an alternative for young children