Contents Leading article The diabetic foot: a major problem for the new millennium ( also available as 'Online PDF file' which can be read in Adobe Acrobat Reader, a no-cost program.) Clinical reviews ( also available as 'Online PDF file' which can be read in Adobe Acrobat Reader, a no-cost program.) A new basal insulin Microangiopathy in Type 1 diabetes: early onset and late protection Cost-effectiveness of tightly controlling Type 2 diabetes Vitamin D and Type 1 diabetes Improved dyslipidaemia with a statin-fibrate combination Troglitazone decreases PAI-1 levels in obese diabetic patients Diabetes complications and superoxide Rosiglitazone monotherapy in Type 2 diabetes: a short-term, dose-ranging study